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Over-the-counter Metronidazole 250 mg can be purchased without a prescription and is most often used to treat symptoms of bacterial infections that may not require the direct supervision of a physician. Metronidazole is an antibiotic OTC medication available as generic flagyl at online pharmacy OverTheCounterPharma.com.

Metronidazole (Generic Flagyl) is amebicidal, trichomonacidal and bactericidal. It belongs to the class of medications called antibiotics. Generic Flagyl is used for the treatment of infections caused by certain bacteria. It is most commonly used for abdominal, vaginal, and intestinal infections, including giardiasis, gastritis, inflammatory bowel disease and balantidiasis, among others.

Generic Flagyl
Metronidazole 200/400mg

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Metronidazole Indications

Metronidazole is not active against fungi, viruses and most other aerobic or facultative anaerobic bacteria, i.e., Actinomyces, Lactobacillus and P. acnes. It is prescribed for the treatment of serious infections caused by susceptible anaerobic bacteria, such as B. fragilis (and other species of Bacteroides), Clostridium, Fusobacterium, Peptococcus, and Peptostreptococcus species. Metronidazole has been used orally in the treatment of antibiotic-induced diarrhea and colitis, including mild to moderate cases of pseudomembranous colitis caused by C. difficile. Metronidazole is used in the treatment of acute necrotizing ulcerative gingivitis and Trichomonal infections in men and women.

Common side effects of Metronidazole

Taking metronidazole 250 mg tablets three times per day can cause some common side effects that are not generally serious. Stools can become loose and watery, resulting in diarrhea. The opposite problem--constipation--may also occur. The drug may cause nausea and vomiting. Combined, these side effects may cause a loss of appetite. Drugs.com states that all of these problems should disappear on their own as your body gets used to metronidazole. Metronidazole 250mg also may induce some problems such as headaches when you first take the pills. You also may experience vertigo or dizziness from the medication. Other non-serious and common side effects that may occur as you first take metronidazole include a metallic taste in the mouth, and a brownish-red or dark urine.


When metronidazole is used in the treatment of acute intestinal amebiasis and amebic liver abscess caused by E. histolytica, sequential treatment with an intraluminal amebicide (such as iodoquinol or paromomycin) is recommended. Metronidazole is not indicated in cases of asymptomatic amebiasis, as it has limited activity against encysted E. histolytica. Patients with severe hepatic disease metabolize metronidazole slowly with resultant accumulation of metronidazole and its metabolites in the plasma.

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